The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2000

Filed:

Jan. 27, 1994
Applicant:
Inventors:

Jacqueline F Aitken, Louisville, CO (US);

Izydor Z Apostol, Boulder, CO (US);

Julie A Lippincott, Boulder, CO (US);

Joseph D Levine, Louisville, CO (US);

Assignee:

Somatogen, Inc., Boulder, CO (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; C07K / ;
U.S. Cl.
CPC ...
435 691 ; 4351721 ; 4352523 ; 4353201 ; 530350 ; 530385 ;
Abstract

This invention relates to proteins with N-terminal modifications in their amino acid sequence that reduce or eliminate the methylation of the N-terminal methionine that occurs when such proteins are produced in bacteria such as E. coli.


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