The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2000
Filed:
May. 01, 1998
Applicant:
Inventors:
Mauro Magnani, Urbino, IT;
Ivo Panzani, Mirandola, IT;
Leonardo Bigi, Mirandola, IT;
Andrea Zanella, Mirandola, IT;
Assignee:
Dideco, S.p.A., Mirandola, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ;
U.S. Cl.
CPC ...
424 9373 ; 424 931 ; 424 933 ; 424 937 ; 435-2 ;
Abstract
A method and apparatus for the encapsulation of biologically active agents in red blood cells (RBCS) is disclosed. The method is characterized in that lysed and partially lysed RBCs are concentrated prior to the introduction of the biologically active agent. The resultant carrier RBCs are stable for an extended period of time under physiological conditions and can be used for the systemic or targeted delivery of therapeutically effective amounts of one or more biologically active agents to a patient.