The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2000
Filed:
Apr. 07, 1999
Applicant:
Inventors:
Gary H Posner, Baltimore, MD (US);
Michael H Parker, Baltimore, MD (US);
Mikhail Krasavin, Baltimore, MD (US);
Theresa A Shapiro, Baltimore, MD (US);
Assignee:
Johns Hopkins University, Baltimore, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61P / ; C07D / ;
U.S. Cl.
CPC ...
514450 ; 514730 ; 514784 ; 514311 ; 514314 ; 514422 ; 514428 ; 514444 ; 514461 ; 546152 ; 546174 ; 548517 ; 548526 ; 549 60 ; 549368 ; 549472 ; 549473 ;
Abstract
Biologically-active, water soluble, 3-substituted trioxanes of the formula ##STR1## wherein R represents a COOH-- substituted aryl group, a substituted or unsubstituted heteroaryl group or an alkyl group, and C.sub.12 -(p-carboxy)benzyloxy trioxanes of formula ##STR2## wherein R represents a substituted or unsubstituted alkyl, alkenyl, aryl or heteroaryl group and methods for their use as antiparasitic agents, particularly for the treatment of malaria.