The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2000
Filed:
Mar. 09, 1998
Takeda Chemical Industries, Ltd., Osaka, JP;
Abstract
Provided is a non-human animal in which an exogeneous gene, a mutant gene thereof of a monocyte chemoattractant protein and/or a receptor thereof is introduced. The present transgenic animals can be utilized as a pathologic model animal for heart diseases, respiratory diseases, joint diseases, kidney diseases, arteriosclerosis, psoriasis, hyperlipidemia, allergic diseases, bone diseases, blood diseases, cerebrovascular disorders, traumatic cerebral disorders, infections diseases, demantia or chroric inflammatory diseases etc. Thus, it is possible to elucidate the mechanism of pathogenesis of these diseases, to determine therapies, and to screen for candidate compounds for the purpose of research and development of therapeutic drugs.