The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2000
Filed:
Dec. 11, 1997
Applicant:
Inventor:
Julianna Lisziewicz, Bethesda, MD (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435455 ; 435456 ; 435458 ; 435325 ;
Abstract
The subject invention provides methods for improving the efficiency of gene transfer to a target cell. The methods are particularly advantageous in that they facilitate the transduction of quiescent cells. In a preferred embodiment the efficiency of gene transfer using a viral vector is enhanced by transiently loading the dytosol of the target cell with dNTP and by transiently adding viral receptors to the surface of the target cell.