The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2000

Filed:

May. 01, 1998
Applicant:
Inventors:

Patricia A Billing-Medel, Gurnee, IL (US);

Maurice Cohen, Highland Park, IL (US);

Tracey L Colpitts, Round Lake, IL (US);

Paula N Friedman, Deerfield, IL (US);

Julian Gordon, Lake Bluff, IL (US);

Edward N Granados, Vernon Hills, IL (US);

Steven C Hodges, Buffalo Grove, IL (US);

Michael R Klass, Libertyville, IL (US);

Jon D Kratochvil, Kenosha, WI (US);

Lisa Roberts-Rapp, Gurnee, IL (US);

John C Russell, Pleasant Prairie, WI (US);

Stephen D Stroupe, Libertyville, IL (US);

Hong Yu, Buffalo Grove, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12P / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435 912 ; 536 231 ; 536 243 ;
Abstract

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as PS108 and transcribed from prostate tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the prostate, such as prostate cancer. Also provided are antibodies which specifically bind to PS108-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PS108 polypeptide, which molecules are useful for the therapeutic treatment of prostate diseases, tumors or metastases.


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