The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2000
Filed:
Nov. 20, 1998
Applicant:
Inventors:
Anuschirwan Peyman, Kelkheim, DE;
Eugen Uhlmann, Glashutten, DE;
Gerhard Breipohl, Frankfurt, DE;
Holger Wallmeier, Sulzbach, DE;
Assignee:
Hoechst Aktiengesellschaft, Frankfurt am Main, DE;
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; C12Q / ; C12Q / ; C07H / ; C07H / ;
U.S. Cl.
CPC ...
514 44 ; 514-1 ; 435-5 ; 435-6 ; 536 221 ; 536 231 ; 536 243 ; 536 253 ; 536 2532 ;
Abstract
Novel oligonucleotide analogs of the formula [I] are described, ##STR1## in which A, B, D, G, L, P, Q, Q', R.sup.5, R.sup.6, X, Y, Z and n are as defined in the description, which have useful physical, biological and pharmacological properties, as well as a process for their preparation. Their application relates to use as inhibitors of gene expression (antisense oligonucleotides, ribozymes, sense oligonucleotides and triplex-forming oligonucleotides), as probes for the detection of nucleic acids and as auxiliaries in molecular biology.