The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2000

Filed:

Feb. 10, 1999
Applicant:
Inventor:

Stephen C Wardlaw, Old Saybrook, CT (US);

Assignees:

Other;

Wardlaw Partners, LP, Lyme, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436 50 ; 436-8 ; 436165 ; 422 67 ; 422 8205 ; 422102 ; 356244 ; 356246 ; 356440 ;
Abstract

Formed constituents of a quiescent anticoagulated whole blood or other biologic fluid sample are optically analyzed by an optical scanning instrument. The sample is contained in a sample chamber that has a varying through plane thickness. The thickness of any fields of view in the blood sample which contain plasma lacunae can be calculated by the instrument as a function of signal emission strength emanating from the colored plasma in the lacunae. The signal emissions can be the result of sample fluorescence or can be the result of signal density emanating from the sample. Particle volumes can be measured as a function of signal emission suppression which is caused by formed particles in the blood sample. The scanning instrument is calibrated by means of the inclusion of a calibration area associated with the chamber which calibration area includes a portion which receives a known depth of colored plasma from the blood sample, and which calibration area also includes a colorant-emission-suppressing feature which feature has a known volume. The scanning instrument scans the known depth portion of the calibration area to determine what degree of signal emission strength correlates to the known depth, and the scanning instrument also scans the colorant-emission-suppressing feature to determine what degree of signal suppression correlates to the known volume of the aforesaid feature. The instrument stores the information gained from the calibration area and then proceeds to analyze the blood sample for formed constituent volumes and constituent counts per unit of the blood sample.


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