The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2000
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Pavel Novotny, deceased, late of Beckenham, GB;
by Jaroslava Novotny, administrator, Bromley, GB;
Juan Antonio Crespo, Naucalpan, MX;
Juraj Ivanyi, London, GB;
Assignee:
Medeva Pharma Limited, Leatherhead, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
435 711 ; 435 712 ; 4351739 ; 435272 ; 4242401 ; 4242541 ; 4242531 ; 4242341 ; 4241841 ; 530412 ; 530413 ; 530825 ;
Abstract
A method of deriving an antigen from Bordetella pertussis, wherein the antigen is characterized by the following features: a relative molecular weight of about 67,000 to 73,000 as determined by 12%(w/w) polyacrylamide gel electrophoresis and a proline:glutamic acid ratio of about 1:1 as determined by amino acid analysis. The method comprises: (a) culturing Bordetella pertussiscells; (b) treating the culture of (a) to obtain an outer membrane fraction; and (c) isolating the antigen from the outer membrane fraction of (b).