The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2000

Filed:

Sep. 21, 1998
Applicant:
Inventors:

Joel Morris, Kalamazoo, MI (US);

Wade J Adams, Kalamazoo, MI (US);

Janice M Friis, Mattawan, MI (US);

Donn G Wishka, Kalamazoo, MI (US);

Assignee:

Pharmacia & Upjohn Company, Kalamazoo, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
514274 ; 5142325 ; 5142322 ; 5142338 ; 5142342 ; 5142345 ; 5142358 ; 51425214 ; 5142278 ; 5142282 ; 5142285 ; 51425216 ; 51425217 ; 514256 ; 514257 ; 514258 ; 514259 ; 514261 ; 514266 ; 544315 ; 544264 ; 544278 ; 544316 ; 544296 ; 544255 ; 544317 ; 544256 ; 544262 ; 544318 ; 544295 ; 544121 ; 544253 ; 544122 ; 544115 ; 544116 ; 544123 ; 544 80 ; 544117 ; 544 586 ; 544 81 ; 544118 ; 544 90 ; 544 61 ;
Abstract

The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula I ##STR1## and pyrimidine-thioalkyl and alkylethers of Formula I, where R.sub.4 is selected from the group consisting of --H or --NR.sub.15 R.sub.16 where R.sub.15 is --H and R.sub.16 is --H, C.sub.1 -C.sub.6 alkyl, --NH.sub.2 or R.sub.15 and R.sub.16 taken together with the --N form 1-pyrrolidino, 1-morpholino or 1-piperidino; and


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