The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2000
Filed:
May. 20, 1998
Beate Heym, Ville d'Avray, FR;
Stewart Cole, Clamart, FR;
Douglas Young, Ruislip, GB;
Ying Zhang, London, GB;
Nadine Honore, Colombes, FR;
Amalio Telenti, Gerzensee, CH;
Thomas Bodmer, Ersigen, CH;
Institut Pasteur, Paris, FR;
Medical Research Council, London, GB;
Assistance Publique, Paris, FR;
Universite Pierre et Marie Curie (Paris VI), Paris, FR;
Universite de Berne, Berne, CH;
Abstract
A nucleotide sequence encoding a katG/lacZ fusion protein is useful for assaying the enzymatic activity of the katG gene product. A process of selecting a compound that is toxic against an isoniazid-resistant mycobaterial strain comprises incubating a catalase peroxidase enzyme with an isoniazid to produce a compound that restores isoniazid susceptability to the isoniazid-resistant mycobaterial strain.