The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2000

Filed:

Oct. 30, 1998
Applicant:
Inventors:

Jinkang Wang, San Francisco, CA (US);

Ralph Niven, Redwood City, CA (US);

Yilin Zhang, San Mateo, CA (US);

Pingzhong Huang, Apex, NC (US);

Assignee:

Megabios Corporation, Burlingame, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; A61K / ;
U.S. Cl.
CPC ...
5483501 ; 424450 ; 435-6 ; 435 691 ; 435 701 ; 435 911 ; 4351721 ; 4353201 ; 435375 ; 4583491 ; 514400 ; 514 44 ;
Abstract

Compounds of the formula: ##STR1## are provided, in which R.sup.1 and R.sup.2 each independently represent a C.sub.8 -C.sub.24 saturated or unsaturated hydrocarbon chain, which is optionally interrupted by from 1 to 3 heteroatom moieties, such as --O--, --S--, --NH-- and --NR--. The symbol X represents --CH.sub.2 --, --O--, --S--, --NH-- or --NR--. The R group for each of the --NR-- moieties represents an alkyl group having from 1 to 4 carbon atoms. Finally, the subscript n represents the integer 1 or 2, and A.sup.- represents an anion, preferably chloride or citrate.


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