The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2000
Filed:
Aug. 26, 1997
Neil Gregory Almstead, Loveland, OH (US);
Biswanath De, Cincinnati, OH (US);
Rimma Sandler Bradley, Fairfield, OH (US);
Garry Steven Garrett, Cincinnati, OH (US);
John Emory Marlin, II, Bridgewater, NJ (US);
John McMillan McIver, Cincinnati, OH (US);
Zhe Wang, Hockessin, DE (US);
Yetunde Olabisi Taiwo, West Chester, OH (US);
The Procter & Gamble Company, Cincinnati, OH (US);
Abstract
The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I) ##STR1## as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable alkoxyamide, ester, acyloxyamide, or imide thereof. Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.