The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2000

Filed:

Aug. 26, 1997
Applicant:
Inventors:

Stanislaw Pikul, Mason, OH (US);

Neil Gregory Almstead, Loveland, OH (US);

Rimma Sandler Bradley, Fairfield, OH (US);

Kelly Lynn McDow-Dunham, Loveland, OH (US);

Biswanath De, Cincinnati, OH (US);

Michael George Natchus, Glendale, OH (US);

Yetunde Olabisi Taiwo, West Chester, OH (US);

Thomas Lee Cupps, Norwich, NY (US);

Assignee:

The Procter & Gamble Company, Cincinnati, OH (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514218 ; 514221 ; 540487 ; 540492 ; 540500 ; 540502 ; 540503 ; 540504 ; 540506 ; 540507 ; 540508 ; 540509 ; 540510 ; 540542 ; 540543 ; 540567 ; 540568 ; 540569 ; 540570 ; 540572 ; 540573 ; 540575 ;
Abstract

The invention provides compounds of formula ##STR1## as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.


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