The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2000
Filed:
Aug. 18, 1997
Applicant:
Inventors:
Marc Hendriks, Brunssum, NL;
Michel Verhoeven, Maastricht, NL;
Patrick Cahalan, Geleen, NL;
Raymond Zeeman, Twente, NL;
Piet Dijkstra, Twente, NL;
Jan Feijen, Twente, NL;
Assignee:
Medtronic, Inc., Minneapolis, MN (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61F / ;
U.S. Cl.
CPC ...
530356 ; 530840 ; 525 541 ; 623 11 ; 623 12 ; 623900 ; 623901 ;
Abstract
Bioprosthetic devices made of collagen-based material having collagen amine groups and collagen carboxyl groups are provided as well as methods for their formation. The methods comprise combining an epoxy functionalized crosslinking agent with the collagen-based material in an aqueous medium at an acidic pH to react a portion of the collagen carboxyl groups with the epoxy functionalized crosslinking agent to form crosslinked collagen-based material comprising residual collagen carboxyl groups.