The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2000
Filed:
Feb. 21, 1997
Applicant:
Inventors:
Khashayar Karimian, Mississauga, CA;
Tim F Tam, Woodbridge, CA;
Denis Desilets, St-Jean-Sur-Richelieu, CA;
Sue Lee, Cedar Knolls, NJ (US);
Tullio Cappelletto, North York, CA;
Wanren Li, Etobicoke, CA;
Assignee:
Apotex Inc., Ontario, CA;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
548130 ; 548128 ; 548129 ; 568 26 ;
Abstract
Thiols are trapped, and converted to disulfide compounds, by a process of reacting them with compounds containing a 1,2,4-thiadiazole ring structure carrying a substituent at position 3 of the thiadiazole ring, and being unsubstituted at position N-2. The process is useful pharmacologically, in inhibiting certain thiol-containing enzymes such as H.sup.+ /K.sup.+ -ATPase (the proton pump), and industrially, in selective removal of thiol compounds from gas or liquid mixtures.