The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2000

Filed:

Aug. 11, 1999
Applicant:
Inventors:

Stephanie L Castro, Columbus, OH (US);

Emilio Barbera-Guillem, Powell, OH (US);

Assignee:

BioCrystal Ltd., Westerville, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; B05D / ; B32B / ; B32B / ; H01L / ;
U.S. Cl.
CPC ...
42840224 ; 428404 ; 257 65 ; 257614 ; 257642 ; 424-91 ; 424-932 ; 424-936 ; 424-942 ; 424-96 ; 4272133 ; 427214 ; 427215 ; 427220 ;
Abstract

Provided are compositions comprising water-soluble, functionalized nanocrystals. The water-soluble functionalized nanocrystals comprise quantum dots capped with a layer of a capping compound, and further comprise, by operably linking and in a successive manner, one or more additional compounds. The one or more additional compounds is comprised of at least a diaminocarboxylic acid which is operatively linked to the capping compound, and may further comprise an amino acid, an affinity ligand, or a combination thereof. Also provided are methods of using the functionalized nanocrystals having an affinity ligand to detect the presence or absence of a target substrate in a sample. The method comprises contacting the functionalized nanocrystals with the sample so that complexes are formed between the functionalized nanocrystals and substrate, if the substrate is present; exposing the complexes in the detection system to a wavelength of light suitable for exciting the functionalized nanocrystals of the complexes to emit a luminescence peak; and detecting the emitted luminescence peak.


Find Patent Forward Citations

Castro, Stephanie. (2000). Functionalized nanocrystals and their use in detection systems (U.S. Patent No. 6114038). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6114038

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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