The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2000
Filed:
Oct. 31, 1997
Applicant:
Inventors:
James A Laugharn, Jr, Winchester, MA (US);
Robert A Hess, Cambridge, MA (US);
Feng Tao, Boston, MA (US);
Assignee:
BBI BioSeq, Inc., West Bridgewater, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 254 ; 536 2541 ; 422 99 ; 203-1 ; 203-2 ; 203 34 ; 203 35 ; 204193 ; 204194 ; 20429825 ; 204400 ; 204403 ;
Abstract
The invention is based on the discovery that hyperbaric, hydrostatic pressure reversibly alters the partitioning of nucleic acids between certain adsorbed and solvated phases relative to partitioning at ambient pressure. The new methods and devices disclosed herein make use of this discovery for highly selective and efficient, low salt isolation and purification of nucleic acids from a broad range of sample types, including forensic samples, blood and other body fluids, and cultured cells.