The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2000

Filed:

Oct. 08, 1997
Applicant:
Inventors:

Maurice Cohen, Highland Park, IL (US);

Paula N Friedman, Deerfield, IL (US);

Julian Gordon, Lake Bluff, IL (US);

Steven C Hodges, Buffalo Grove, IL (US);

Michael R Klass, Libertyville, IL (US);

Jon D Kratochvil, Wildwood, MO (US);

Lisa Roberts-Rapp, Gurnee, IL (US);

John C Russell, Pleasant Prairie, WI (US);

Stephen D Stroupe, Libertyville, IL (US);

Hong Yu, Buffalo Grove, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ; C12P / ; G01N / ; C07H / ;
U.S. Cl.
CPC ...
435-6 ; 435-723 ; 435 912 ; 435 915 ; 435 9151 ; 436504 ; 536 2431 ; 536 2433 ; 536 245 ; 536 231 ;
Abstract

A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as PS112 and transcribed from prostate tissue is described. A fully sequenced clone representing a continuous sequence of PS112 is also disclosed. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the prostate, such as prostate cancer. Also provided are antibodies which specifically bind to PS112-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PS112 polypeptide, which molecules are useful for the therapeutic treatment of prostate diseases, tumors or metastases.


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