The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2000

Filed:

Sep. 23, 1998
Applicant:
Inventors:

Hendrik Timmerman, Voorschoten, NL;

Mingqiang Zang, Scotland, GB;

Kazuhiro Onogi, Iruma, JP;

Yoshio Takahashi, Iruma, JP;

Masahiro Tamura, Higashimurayama, JP;

Tsutomu Tohma, Higashimurayama, JP;

Yasushi Wada, Tachikawa, JP;

Jiro Matsumoto, Sayama, JP;

Toru Kanke, Higashimurayama, JP;

Assignee:

Kowa Co., Ltd., Nagoya, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514314 ; 514312 ; 514307 ; 514309 ; 5142242 ; 514213 ; 540523 ; 540594 ; 544 51 ; 546158 ; 546165 ; 546176 ;
Abstract

The present invention is directed to a piperidine derivative represented by the following formula (1) or a salt thereof: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 individually represent hydrogen atoms, etc., Y represents ##STR2## B represents a single bond, an alkylene group, --S--CH.sub.2 --, or --CH.dbd.CH--, E represents a single bond or a trimethylene group, Z represents an oxygen atom, etc., and n represents a number between 2 and 5 inclusive; and to a medicine containing the compound. The medicine according to the present invention is endowed with excellent anti-histaminic activity and antileukotriene activity, and exhibits reduced side effects such as drowsiness.


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