The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 22, 2000

Filed:

Aug. 05, 1997
Applicant:
Inventors:

Paul Edward Aldrich, Wilmington, DE (US);

Argyrios Georgios Arvanitis, Kennett Square, PA (US);

Rajagopal Bakthavatchalam, Wilmington, DE (US);

James Peter Beck, Smyrna, DE (US);

Robert Scott Cheeseman, Newtown Square, PA (US);

Robert John Chorvat, West Chester, PA (US);

Paul Joseph Gilligan, Wilmington, DE (US);

Carl Nicholas Hodge, Wilmington, DE (US);

Zelda Rakowitz Wasserman, Wilmington, DE (US);

Assignee:

Dupont Pharmaceuticals Company, Wilmington, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K / ;
U.S. Cl.
CPC ...
514258 ; 514267 ; 514259 ; 514254 ; 514241 ; 5142305 ; 5142298 ; 5142342 ; 5142325 ; 5142285 ; 5142268 ; 5142225 ; 514212 ; 514210 ; 544254 ; 544 55 ; 544 56 ; 544-8 ; 544118 ; 544 82 ; 544180 ; 544264 ; 544284 ; 544353 ; 544102 ; 544262 ; 540600 ;
Abstract

The present invention provides novel compounds, compounds and pharmaceutical compositions thereof, and methods of using same in the treatment of affective disorders, anxiety, depression, post-traumatic stress disorders, eating disorders, supranuclear palsy, irritable bowel syndrome, immune suppression, Alzheimer's disease, gastrointestinal diseases, anorexia nervosa, drug and alcohol withdrawal symptoms, drug addiction, inflammatory disorders, or fertility problems. The novel compounds provided by this invention are those of formula: ##STR1## wherein R.sup.1, R.sup.3, R.sup.4, R.sup.5, Z, Y, V, X, X', J, K, L, and M are as defined herein.


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