The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2000
Filed:
Jan. 15, 1998
Lorne M Golub, Smithtown, NY (US);
Thomas F McNamara, Port Jefferson, NY (US);
Nungavaram S Ramamurthy, Smithtown, NY (US);
Hsi-Ming Lee, Setauket, NY (US);
Sanford Simon, Stony Brook, NY (US);
Balakrishna L Lokeshwar, Miami, FL (US);
Marie G Selzer, Fort Lauderdale, FL (US);
Norman L Block, Miami, FL (US);
Other;
Abstract
The invention is a method of inhibiting cancer growth, by inhibiting cellular proliferation, invasiveness, or metastasis, or by inducing cytotoxicity against cancer in mammals. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) and other functionally related chemically modified, preferably non-antibacterial, tetracycline compounds to inhibit cancer growth. The method is particularly effective to inhibit the establishment, growth, and metastasis of solid tumors, such as tumors derived from colon cancer cells, breast cancer cells, melanoma cells, prostatic carcinoma cells, or lung cancer cells.