The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2000
Filed:
Jun. 05, 1995
Applicant:
Inventors:
Michael D Pierschbacher, San Diego, CA (US);
David S Lukeman, Oceanside, CA (US);
Soan Cheng, San Diego, CA (US);
William S Craig, San Diego, CA (US);
Assignee:
La Jolla Cancer Research Foundation, La Jolla, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514 11 ; 514-3 ; 514 12 ; 514 13 ; 514 14 ; 514 15 ; 514 16 ; 514 17 ; 514 18 ; 530317 ; 530324 ; 530325 ; 530326 ; 530327 ; 530328 ; 530329 ; 530330 ;
Abstract
The invention provides RGD containing peptides which are cyclized and contain hydrophobic moieties adjacent the carboxy terminus of the RGD sequence. Such peptides have an high affinity for the receptor IIb/IIIa and low affinity for the fibronectin and vitronectin receptors. Such peptides can be administered in a suitable physiologically acceptable carrier to therapeutically treat thrombosis.