The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2000
Filed:
Jun. 19, 1998
Applicant:
Inventors:
Lawrence S Cousens, Oakland, CA (US);
Christine D Eberhardt, Auburn, WA (US);
Patrick Gray, Seattle, WA (US);
Hai Le Trong, Edmonds, WA (US);
Larry W Tjoelker, Kirkland, WA (US);
Cheryl L Wilder, Seattle, WA (US);
Assignee:
ICOS Corporation, Bothell, WA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
424 946 ; 435195 ; 435196 ; 435197 ;
Abstract
The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events. Specifically disclosed are methods for the treatment of reperfusion injury using platelet-activating factor acetylhydrolase products.