The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2000
Filed:
Oct. 14, 1997
Applicant:
Inventors:
Robert William Van Holten, Flemington, NJ (US);
Gilbert J Quinton, Belle Meade, NJ (US);
George E Oulundsen, Jr, Nashua, NH (US);
Assignees:
Ortho Diagnostic Systems, Inc., Raritan, NJ (US);
Millipore Corporation, Bedford, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
5303901 ; 4241731 ; 4241761 ; 5303896 ; 530414 ;
Abstract
Methods for producing immunoglobulins and in particular anti-D immunoglobulin substantially free of virus and product resulting therefrom. Specifically provided are methods for nanofiltration of the anti-D immunoglobulin in high ionic strength buffer and with excipient such as polysorbate 80. Additional steps include diafiltration to concentrate the anti-D protein and reduce the concentration of excipient present.