The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2000

Filed:

Jul. 28, 1998
Applicant:
Inventors:

Olga Bandman, Mountain View, CA (US);

Roger Coleman, Mountain View, CA (US);

Janice Au-Young, Berkeley, CA (US);

Lynn E Murry, Portola Valley, CA (US);

Assignee:

Incyte Pharmaceuticals, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
424 851 ; 530351 ; 435 695 ; 435 712 ; 435471 ; 435325 ; 4352523 ; 4353201 ; 536 235 ;
Abstract

The present invention provides novel monocyte activating cytokine (MAC) and a polynucleotide encoding MAC. The invention also provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding MAC. The invention also provides for the production and use of substantially purified MAC in pharmaceutical compositions for the treatment of cancer and disease of the immune system. The invention also describes diagnostic assays which utilize the polynucleotide to hybridize with the transcripts encoding MAC and antibodies which specifically bind to MAC.


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