The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2000

Filed:

Feb. 12, 1999
Applicant:
Inventors:

George Phillip Vlasuk, Carlsbad, CA (US);

Patrick Eric Stanssens, St-Martens-Latem, BE;

Joris Hilda Messens, Dilbeek, BE;

Marc Josef Lauwereys, Haaltert, BE;

Yves Rene LaRoche, Brussels, BE;

Laurent Stephane Jespers, Tervuren, BE;

Yannick Georges Gansemans, Ichtegem, BE;

Matthew Moyle, Boulder, CA (US);

Peter W Bergum, San Diego, CA (US);

Assignee:

Corvas International, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ;
U.S. Cl.
CPC ...
536 235 ;
Abstract

Proteins which have activity as anticoagulants and/or serine protease inhibitors and have at least one NAP domain and are described. Certain of these proteins have factor Xa inhibitory activity and others have activity as inhibitors of factor VIIa/TF. These proteins can be isolated from natural sources as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.


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