The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2000

Filed:

Oct. 31, 1997
Applicant:
Inventors:

Dange Veerapaneni, San Diego, CA (US);

Shoji Hamanaka, Kanagawa, JP;

Iwao Nozawa, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C12Q / ; C12N / ;
U.S. Cl.
CPC ...
435375 ; 435-6 ; 435 9131 ; 4353201 ; 435325 ; 435366 ; 435455 ; 536 231 ; 536 232 ; 536 2431 ; 536 2433 ; 536 245 ;
Abstract

Enzymatic RNA molecules which cleave mRNA encoding IL-15, are provided. The constructs of the invention include regulatory regions for expression in cells, cell lines, or transgenic non-human animals. The ribozymes of the invention are directed against IL-15 mRNA and are useful in treating rheumatoid arthritis.


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