The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2000

Filed:

Oct. 31, 1997
Applicant:
Inventors:

Gregory E Hardee, Rancho Sante Fe, CA (US);

Richard S Geary, Carlsbad, CA (US);

Arthur Levin, Rancho Sante Fe, CA (US);

Michael V Templin, Carlsbad, CA (US);

Randy Howard, Encinitas, CA (US);

Rahul C Mehta, San Marcos, CA (US);

Assignee:

Isis Pharmaceuticals Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ; C07H / ; C12N / ;
U.S. Cl.
CPC ...
514 44 ; 435-6 ; 435455 ; 435375 ; 435377 ; 536 231 ; 536 241 ; 536 245 ;
Abstract

Pharmaceutical compositions comprising sterically stabilized liposomes containing antisense oligonucleotides are provided for the modulation of expression of the human ras gene in both the normal (wildtype) and activated (mutant) forms.


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