The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2000
Filed:
Sep. 25, 1998
Kenneth B Marcu, Stony Brook, NY (US);
The Research Foundation of the State University of New York, Albany, NY (US);
Abstract
The present invention provides an isolated I.kappa.B kinase designated IKK.alpha..DELTA.C, that regulates NF.kappa.B gene transcription. IKK.alpha..DELTA.C is an I.kappa.B protein kinase having a kinase domain, a leucine zipper like .alpha.-helix domain, and no helix-loop-helix domain. Also provided are the amino acid sequence of IKK.alpha..DELTA.C, the nucleotide sequence encoding IKK.alpha..DELTA.C, and other related protein and nucleic acid molecules. The invention provides antibodies specific for IKK.alpha..DELTA.C and methods of using the IKK.alpha..DELTA.C proteins of the invention in the development of antiinflammatory agents or immunosuppressants.