The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2000

Filed:

Jun. 06, 1995
Applicant:
Inventors:

Antonello Covacci, Siena, IT;

Massimo Bugnoli, Monteriggioni, IT;

John Telford, Monteriggioni, IT;

Giovanni Macchia, Avezzano, IT;

Rino Rappuoli, Quercegrossa, IT;

Assignee:

Chiron Corporation, Emeryville, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07H / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
435325 ; 435-6 ; 435 693 ; 435 701 ; 435 711 ; 435 712 ; 435 912 ; 4353201 ; 530350 ; 42419711 ; 4241901 ; 514 44 ; 536 237 ;
Abstract

Helicobacter pylori known to cause or be a cofactor in type B gastritis, peptic ulcers, and gastric tumors. In both developed and developing countries, a high percentage of people are infected with this bacterium. The present invention relates generally to certain H. pylori proteins, to the genes which express these proteins, and to the use of these proteins for diagnostic and vaccine applications. Specifically, molecular cloning, nucleotide, and amino add sequences for the H. pylori cytotoxin (CT), the 'Cytotoxin Associated Immunodominant' (CAI) antigen, and the heat shock protein (hsp60) are described herein.


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