The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 13, 2000
Filed:
Mar. 31, 1999
Applicant:
Inventors:
Tomio Takeuchi, Tokyo, JP;
Sumio Umezawa, Tokyo, JP;
Tsutomu Tsuchiya, Yokohama, JP;
Yasushi Takagi, Yokohama, JP;
Assignee:
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ;
U.S. Cl.
CPC ...
536 175 ; 536-41 ; 536-64 ; 536 172 ; 536 185 ; 536 187 ; 536124 ;
Abstract
7-O-(4-Amino-2,4,6-trideoxy-2-fluoro-.alpha.-L-mannopyranosyl)-daunomycinon e or -adriamycinone is now synthesized as a daunomycinone or adriamycinone derivative having the general formula ##STR1## wherein R is a hydrogen atom or hydroxyl group. These novel compounds according to this invention exhibit excellent antitumor activities and have a high solubility in water, and hence they are useful as an antitumor agent.