The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2000

Filed:

Dec. 07, 1994
Applicant:
Inventors:

Louis J Theodore, Lynnwood, WA (US);

Donald B Axworthy, Brier, WA (US);

John M Reno, Brier, WA (US);

Assignee:

NeoRx Corporation, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ;
U.S. Cl.
CPC ...
514 23 ; 514 24 ; 514 25 ; 514 54 ; 514 61 ; 514 62 ;
Abstract

Small molecule weight clearing agents containing ligands such as biotin or biotin analogs and hexose residue, in particular galactose or N-acetyl galactosamine residues are taught. These clearing agents effectively clear anti-ligand containing conjugates in vivo via hepatocyte receptor mediated clearance mechanisms.


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