The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2000
Filed:
Dec. 31, 1997
Applicant:
Inventors:
Paul F Jackson, Bel Air, MD (US);
Weixing Li, Baltimore, MD (US);
Keith M Maclin, Baltimore, MD (US);
Kevin L Tays, Elkridge, MD (US);
Takashi Tsukamoto, Baltimore, MD (US);
Barbara S Slusher, Kingsville, MD (US);
Assignee:
Guilford Pharmaceuticals Inc., Baltimore, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C07F / ; A61K / ;
U.S. Cl.
CPC ...
514574 ; 562-8 ; 562 10 ; 562 24 ; 514 75 ;
Abstract
The present invention relate to phosphinic alkanoic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase activity and to treat glutamate abnormalities and prostate diseases.