The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2000

Filed:

Jun. 26, 1997
Applicant:
Inventors:

Abraham Nudelman, Rehovot, IL;

Ada Rephaeli, Herzelia, IL;

Assignees:

Bar-Ilan University, Ramat-Gan, IL;

Mor Rese Applications, Givat Shmuel, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514277 ; 514548 ; 546342 ; 554221 ;
Abstract

This invention relates to the novel retinoyloxy(aryl-substituted)-alkylene butyrate compounds of Formula (I) and pharmaceutical compositions containing same, to methods of treating, preventing or ameliorating cancer and other proliferative diseases in a subject in need of such treatment comprising administering a compound of Formula (I) and pharmaceutically-acceptable salts and prodrugs thereof. ##STR1## The compounds of the invention are also useful in methods of inhibiting histone deacetylase, ameliorating wrinkles, treating or ameliorating dermatological disorders, inducing wound healing, treating cutaneous ulcers and treating gastrointestinal disorders.


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Nudelman, Abraham. (2000). Retinoyloxy aryl-substituted alkylene butyrates useful for the treatment (U.S. Patent No. 6071923). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6071923

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