The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2000
Filed:
May. 06, 1997
Applicant:
Inventors:
Randall W Barton, Farmington, CT (US);
Charles A Kennedy, Southbury, CT (US);
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
435-71 ; 435-794 ; 530352 ; 53038826 ; 4241461 ;
Abstract
This invention relates to phosphotyrosine mimics which, when incorporated into an appropriate molecular structure, are capable of inhibiting the binding of tyrosine kinase-dependent regulatory proteins to the native phosphotyrosine-containing receptors. This invention also relates to methods and kits for identifying and using phosphotyrosine mimics. The compounds, kits and methods of this invention are useful for identifying and designing antagonists of tyrosine-kinase dependent regulatory proteins, such as signal transduction proteins containing SH.sub.2 binding domains.