The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2000

Filed:

Apr. 23, 1997
Applicant:
Inventors:

Andrea Leone-Bay, Ridgefield, CT (US);

Koc-Kan Ho, Mt. Kisco, NY (US);

Jeffery Bruce Press, Brewster, NY (US);

Nai-Fang Wang, Long Island, NY (US);

Assignee:

Emisphere Technologies, Inc., Tarrytown, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07C / ;
U.S. Cl.
CPC ...
424 852 ; 424 854 ; 4241411 ; 4241841 ; 514-2 ; 514-3 ; 514 11 ; 514 12 ; 514 21 ; 514 56 ; 514773 ; 514784 ; 546323 ; 548537 ; 549 72 ; 554 94 ; 554106 ; 554111 ; 554112 ; 562430 ; 562444 ; 562449 ; 562450 ; 562507 ; 562567 ;
Abstract

The present invention provides modified amino acids for delivering active agents, and particularly biologically or chemically active agents. The preferred modified amino acids of the present invention include N-acylated or sulfonated amino acids. These modified amino acids are used as carriers to facilitate the delivery of a cargo to a target. Such modified amino acids are well suited to form non-covalent mixtures with biologically-active agents for oral administration to animals. Methods for the preparation and administration of the modified amino acids and compositions including the same are also provided.


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