The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2000
Filed:
Dec. 19, 1997
Applicant:
Inventors:
Joanna Chmielewska, Stockholm, SE;
Tomas Lundqvist, Goteborg, SE;
Erifili Masialou, Stockholm, SE;
Derek Ogg, Stockholm, SE;
Assignee:
Pharmacia & Upjohn AB, Stockholm, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C12N / ; C07K / ;
U.S. Cl.
CPC ...
530381 ; 424 8464 ; 435 686 ; 530380 ;
Abstract
The present invention is directed to a modified coagulation factor Xa which has an improved capacity of forming crystals compared to its native form. Such crystals or crystalline composition are especially useful for studies in crystalline form of the active catalytic site of factor Xa when it is complexed to a specific affinity ligand with inhibiting characteristics.