The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2000
Filed:
Aug. 17, 1999
Knud Erik Andersen, Smorum, DK;
Tine Krogh Jo slashed.rgensen, .O slashed.lstykke, DK;
Rolf Hohlweg, Kvistgaard, DK;
Erik Fischer, Copenhagen S, DK;
Uffe Bang Olsen, Vallensbek, DK;
Zdenek Polivka, Praha 5, CZ;
Karel Sindelar, Praha 4, CZ;
Vladimir Valenta, Praha 4, CZ;
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
The present invention relates to novel N-substituted azaheterocyclic compounds of the general formula ##STR1## wherein X, Y, Z, R.sup.1, R.sup.2 and r are as defined in the detailed part of the present description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides, e.g. non-insulin-dependent diabetes mellitus (NIDDM) and ageing-associated obesity.