The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2000
Filed:
Feb. 12, 1998
Applicant:
Inventors:
Edmond J LaVoie, Princeton Junction, NJ (US);
Jung Sun Kim, Pusan, KR;
Meera Rangarajan, Highland Park, NJ (US);
Leroy Fong Liu, Bridgewater, NJ (US);
Assignee:
Rutgers, The State University of New Jersey, New Brunswick, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514394 ; 5483054 ;
Abstract
The invention provides a topoisomerase poison of formula I: ##STR1## wherein R.sub.1 -R.sub.8 have any of the meanings defined in the specification, or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof.