The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2000
Filed:
May. 14, 1997
Applicant:
Inventors:
Wayne Kindsvogel, Seattle, WA (US);
Eva Pia Reich, Palo Alto, CA (US);
Jane A Gross, Seattle, WA (US);
Assignee:
Anergen, Inc., Redwood City, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
435325 ; 530350 ; 5303871 ; 5303882 ; 53038822 ; 53038875 ; 5303896 ; 5303911 ;
Abstract
A method for preparing a responder cell clone that proliferates when combined with a selected antigenic peptide presented by a stimulator cell is disclosed. CD56 negative, CD8 negative responder cells are isolated from peripheral blood mononucleocytes and stimulated with pulsed or primed stimulator cells. Responder cell clones from prediabetic or new onset diabetic patients which are specific for GAD peptides are also disclosed.