The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2000

Filed:

May. 16, 1997
Applicant:
Inventors:

Leonard Katz, Wheeling, IL (US);

Diane L Stassi, Highland Park, IL (US);

Richard G Summers, Jr, Nashotah, WI (US);

Xiaoan Ruan, Lake Bluff, IL (US);

Ana Pereda-Lopez, Mundelein, IL (US);

Stephan J Kakavas, Buffalo Grove, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ; C07H / ;
U.S. Cl.
CPC ...
435-4 ; 435 32 ; 514 29 ; 536-72 ;
Abstract

The invention provides novel erythromycin derivatives in which methyl groups on the macrolactone ring have been substituted with --H, --Et, and/or --OH. The invention also provides reagents such as isolated polynucleotides, vectors comprising the polynucleotides and host cells transformed with the vectors for making the novel compounds. Methods for making the compounds utilizing genetic engineering techniques are also disclosed.


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