The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2000
Filed:
Apr. 15, 1998
Philippa M Wiggins, Auckland, NZ;
Biostore New Zealand, Ltd, Parnell, NZ;
Abstract
The present invention provides methods for preserving living biological materials by lyophilization that enable cells and tissues to be stored for extended periods of time with minimal loss of biological activity. In one embodiment, the inventive methods comprise contacting a biological material with a preservative solution comprising trimethyl amine oxide, sodium citrate and sodium chloride, reducing the temperature of the biological material to less than 0.degree. C., and drying the biological material to provide a freeze-dried material. The preservative solutions employed in the inventive methods are preferably isotonic with the material to be preserved and substantially free of iodide, dihydrogen phosphate, bicarbonate, nitrate and bisulfate.