Fibrin sealant glue-gun with insertable compressed gas cartridge and

Abstract

An applicator for dispensing a substance comprising first and a second components of any mixture of fluids for either medical or other applications, in an exemplary application, a biological adhesive, such as a fibrin sealant, wherein the applicator comprises a housing having a first dispensing conduit for dispensing the first component and a second dispensing conduit for dispensing the second component. A pressure supply conduit is in communication with the dispensing conduits and both a first reservoir containing the first component, and a second reservoir containing the second component. A cartridge containing a biologically compatible compressed gas may be attached to the pressure supply conduit. The first and second reservoirs may each be provided with a luer fitting to facilitate attachment to a supply of the first component and the second component, respectively. A first pressure regulator, also in communication with the first reservoir, controls the pressure supplied through the pressure supply conduit to the first reservoir and a second pressure regulator, also in communication with the second reservoir, controls the pressure supplied through the pressure supply conduit to the second reservoir. The pressure regulators may be pressure regulating screws or valves, or they may comprise dispensing conduits having various cross sectional areas or reservoir conduits having various cross sectional areas. The applicator dispenses the first and second components, typically a thrombin solution and a fibrinogen solution, in controlled proportions by adjustment of the pressure regulators.