The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2000
Filed:
Jul. 21, 1998
Applicant:
Inventors:
Assignee:
Taogosei Co. Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
536 245 ; 536231 ; 536 243 ; 536 2431 ; 435325 ; 435366 ; 435375 ; 514 44 ;
Abstract
The present invention provides an antisense nucleic acid compound inhibiting expression of vascular endothelial growth factor as well as therapeutic and diagnostic agents comprising the same as an active ingredient. A compound which nucleotide sequence is substantially complementary to a nucleotide sequence located upstream of a translation region in a gene coding for vascular endothelial growth factor and which inhibits 50% or more of the expression of vascular endothelial growth factor in cells is used as the antisense nucleic acid.