The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2000
Filed:
Jun. 14, 1996
Applicant:
Inventors:
Michael B Brenner, Sherborn, MA (US);
Christina M Parker, Arlington, MA (US);
Assignee:
Brigham & Women's Hospital, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
530326 ; 530327 ; 530328 ; 530329 ; 530330 ; 514 13 ; 514 14 ; 514 15 ; 514 16 ; 514 17 ;
Abstract
The present invention relates to a novel integrin .alpha..sup.E subunit and its functional equivalents. The method for screening a molecular library to identify lead compounds which mimick the in vivo activity of an integrin .alpha..sup.E chain is disclosed. The invention further includes pharmaceutical compositions containing the isolated peptides, oligonucleotides encoding the peptides, vectors containing the oligonucleotides, and cell lines transfected with the vectors.