The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2000
Filed:
Jun. 10, 1992
Applicant:
Inventor:
Richard A Glennon, Richmond, VA (US);
Assignee:
Virginia Commonwealth University, Richmond, VA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514649 ; 514651 ; 514652 ; 514653 ; 514654 ; 514655 ; 564342 ; 564344 ; 564345 ; 564347 ; 564348 ; 564352 ; 564353 ; 564354 ; 564355 ; 564360 ; 564361 ; 564366 ; 564373 ; 564378 ; 564381 ; 564382 ; 564383 ;
Abstract
The invention relates to methods for the treatment of central nervous system disorders, gastrointestinal disorders, drug abuse, angina, migraine, hypertension and depression by administering a pharmaceutical composition comprising an effective amount of certain sigma receptor ligands to a patient in need of such treatment. The invention further relates to novel sigma receptor ligands having high binding to the sigma receptor and pharmaceutical compositions thereof. Unexpectedly, certain of the sigma receptor ligands of the present invention have selectivity for the sigma receptor over the DA, PCP and 5-HT.sub.1A receptors.