The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2000
Filed:
Dec. 12, 1994
Applicant:
Inventors:
Elise C Kohn, Olney, MD (US);
Lance A Liotta, Potomac, MD (US);
Kevin L Gardner, Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A01N / ;
U.S. Cl.
CPC ...
514359 ; 514383 ; 514398 ; 514407 ; 514396 ; 514399 ; 514255 ; 514256 ; 514258 ; 514261 ;
Abstract
A class of calcium-response modification compounds is disclosed which inhibits the activation of retroviral LTR promoters, including the HIV-LTR. This class of compounds are used to delay or suppress the transition of a retroviral infection from a latent to a virulent condition, thereby ameliorating retrovirally caused diseases such as AIDS. The compounds are also useful in cancer treatment, allowing for coordinated therapeutic approaches to retroviral diseases and related cancers such as AIDS and Kaposi's Sarcoma. The compounds are also useful in standardizing in vitro assays of clinical and experimental importance.