The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2000
Filed:
Jul. 07, 1997
Applicant:
Inventors:
John Matthew Fevig, Lincoln University, PA (US);
Donald Joseph Pinto, Newark, DE (US);
Mimi Lifen Quan, Newark, DE (US);
Petrus Fredericus Stouten, Wilmington, DE (US);
Assignee:
Dupont Pharmaceutical Co., Wilmington, DE (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514340 ; 514343 ; 514344 ; 514345 ; 514347 ; 514348 ; 514349 ; 514350 ; 514351 ; 514352 ; 514354 ; 514356 ; 514378 ; 514380 ; 514422 ; 514423 ; 514424 ; 514426 ; 514427 ; 514428 ; 514444 ; 514445 ; 514447 ; 514448 ; 514451 ; 514459 ; 514460 ; 514461 ; 514471 ; 514472 ; 514473 ; 5462721 ; 5462764 ; 5462784 ; 5462787 ; 5462791 ; 548240 ; 548243 ; 548244 ; 548517 ; 548518 ; 548519 ; 548521 ; 548530 ; 548531 ; 548532 ; 548541 ; 548546 ; 548547 ; 548548 ; 548550 ; 548556 ; 548557 ; 548560 ; 548561 ; 548562 ; 548565 ; 548566 ; 548568 ; 548570 ; 548571 ; 548572 ; 548577 ; 549 59 ; 549 61 ; 549 62 ; 549 64 ; 549 65 ; 549 66 ; 549 70 ; 549 71 ; 549 72 ; 549 74 ; 549 75 ; 549 76 ; 549 78 ; 549 79 ; 549414 ; 549416 ; 549419 ; 549420 ; 549424 ; 549425 ; 549426 ; 549427 ; 549472 ; 549473 ; 549474 ; 549475 ; 549479 ; 549480 ; 549483 ; 549484 ; 549491 ; 549496 ; 549498 ; 549499 ; 549502 ; 549505 ; 564244 ; 564163 ; 564166 ; 564171 ;
Abstract
The present application describes amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein one of D and D' may be C(.dbd.NH)NH.sub.2 and the other H, and J.sup.1 and J.sup.2 may be O or CH.sub.2, which are useful as inhibitors of factor Xa.