The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2000

Filed:

Oct. 20, 1998
Applicant:
Inventors:

Kochat Haridas, San Antonio, TX (US);

Frederick H Hausheer, Boerne, TX (US);

Assignee:

BioNumerik Pharmaceuticals, Inc., San Antonio, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; A61P / ;
U.S. Cl.
CPC ...
514 63 ; 546 48 ; 546 14 ; 514283 ;
Abstract

Derivatives of Camptothecin are disclosed, particularly derivatives having multiple substitutions at the `A`, `B` and `E` rings thereof. The novel compounds are useful in treating a wide variety of susceptible tumors and are potent inhibitors of Topoisomerase I.


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